What Is hs-CRP?
hs-CRP (high-sensitivity C-reactive protein) is a protein produced by the liver in response to inflammation. The high-sensitivity version detects low-grade chronic inflammation — the kind that predicts cardiovascular disease.
Why Inflammation Matters for Heart Health
Cardiovascular disease is not just a cholesterol problem. Inflammation plays an active role in plaque development and rupture. The JUPITER trial demonstrated that patients with normal LDL but elevated hs-CRP had reduced cardiovascular events when treated with a statin.
hs-CRP Reference Ranges
Below 1.0 mg/L: Low risk. 1.0–3.0: Moderate risk. Above 3.0: High risk. Above 10: Acute inflammation (repeat testing needed).
What Causes Elevated hs-CRP?
- Excess visceral fat — metabolically active and pro-inflammatory
- Poor diet — high refined sugar, processed food
- Physical inactivity
- Chronic stress and poor sleep
- Smoking
- Periodontitis (gum disease)
How to Lower hs-CRP
- Increase omega-3 intake
- Mediterranean-style diet
- Exercise
- Weight loss
- Improved sleep
- Dental care — treating gum disease reduces inflammatory load
Is hs-CRP Tested in a Standard Physical?
No. Stem Health tests hs-CRP in every Core and Horizon Assessment alongside ApoB, Lp(a), and homocysteine.
