Hormonal
5 min read

What Is a Full Thyroid Panel? Beyond TSH | Stem Health

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Published on
22 January 2021

What Is a Full Thyroid Panel?

A full thyroid panel measures:

  • TSH — the pituitary signal to the thyroid
  • Free T4 — the primary thyroid hormone
  • Free T3 — the active form cells actually use
  • TPO antibodies — marker of autoimmune thyroid disease (Hashimoto's)
  • Anti-thyroglobulin antibodies — second autoimmune marker

Most standard physicals test TSH only. That's not the full picture.

Why TSH Alone Is Insufficient

Normal TSH, low Free T3: Your body can't convert T4 to its active form. Symptoms present, TSH looks normal.

Normal TSH, positive antibodies: Early Hashimoto's with active thyroid damage, but TSH hasn't moved yet.

Normal TSH, abnormal Free T4: TSH within range but Free T4 at the low end, correlating with symptoms.

TSH Reference Ranges

Standard range: 0.4–4.5 mU/L. Many clinicians consider functional optimal range to be 1.0–2.5 mU/L. A TSH of 4.0 is "within range" but not the same as 1.5.

Is a Full Thyroid Panel Tested in a Standard Physical?

Rarely. Standard care tests TSH only. Stem Health's Core Assessment includes TSH, Free T3, Free T4, and thyroid antibodies.

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